Acoustofluidics for cell patterning and tissue engineering

Autor: Zhuhao Wu, Meidie Pan, Jinglin Wang, Baojie Wen, Ling Lu, Haozhen Ren
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Engineered Regeneration, Vol 3, Iss 4, Pp 397-406 (2022)
Druh dokumentu: article
ISSN: 2666-1381
DOI: 10.1016/j.engreg.2022.08.005
Popis: Acoustofluidics has been a promising approach using sound waves to manipulate particles and actuate fluids in biomedical applications. It usually generates acoustic radiation force and acoustic streaming to initiate diffraction, reflection and interference, building up a pressure distribution to facilitate accurate manipulation of micro- or nano-scale particles and fluids. Owing to its remarkable contact-free and biocompatible advantages, acoustofluidics has been used in high-throughput cell analysis, size-controllable organoid structures, and functional tissue mimics. We enumerate the basic concepts and the sufficient research of acoustofluidics in precise patterning and tissue engineering in this review, including the design and function of four typical acoustofluidic devices, various forms of cell patterning and 3D tissue engineering. Meanwhile, we outlined current challenges and future directions of acoustofluidics in biomedicine and tissue engineering.
Databáze: Directory of Open Access Journals