Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity
| Autor: | Akshay Shankar, Naveen Kumar Kaushik, Vinod Kumar, Vinay Malik, Davender Singh, Vijay Kumar, Bijender Singh |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Taibah University for Science, Vol 18, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 16583655 1658-3655 |
| DOI: | 10.1080/16583655.2024.2381286 |
| Popis: | In the present study, different parameters, affecting the growth of Thermomyces lanuginosus BJMDU1 and extracellular synthesis of silver nanoparticles (AgNPs), were studied. Culture extract of thermophilic mould Thermomyces lanuginosus BJMDU1 showed potential in green synthesis of silver nanoparticles when the fungus was grown in a sucrose yeast extract medium (pH 8.0) at 45°C. Mycosynthesis of AgNPs was enhanced in the presence of light using 2 mM AgNO3 and 200 µl of culture extract at 50°C. The reaction parameters significantly improved the synthesis of AgNPs. Techniques like UV-Vis & FT-IR spectroscopy, X-ray diffraction, transmission electron microscopy and dynamic light scattering were used to characterise AgNPs. Biogenic nanoparticles showed an absorption peak at 430 nm having 80 nm size. Biogenic AgNPs showed potent antibacterial and antiplasmodial activity with no haemolysis up to 40 µg/ml. The p-nitrophenol was catalytically reduced to p-aminophenol by AgNPs. Therefore, green mycosynthesised AgNPs could be used in the therapeutics and remediation of environmental pollutants. |
| Databáze: | Directory of Open Access Journals |
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