The Role of Inositols in Endocrine and Neuroendocrine Tumors

Autor:	Marilda Mormando, Giulia Puliani, Marta Bianchini, Rosa Lauretta, Marialuisa Appetecchia
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	inositols myo-inositols inositol hexakisphosphate endocrine cancer thyroid cancer neuroendocrine neoplasms Microbiology QR1-502
Zdroj:	Biomolecules, Vol 14, Iss 8, p 1004 (2024)
Druh dokumentu:	article
ISSN:	2218-273X
DOI:	10.3390/biom14081004
Popis:	Inositols have demonstrated a role in cancer prevention and treatment in many kinds of neoplasms. Their molecular mechanisms vary from the regulation of survival and proliferative pathways to the modulation of immunity and oxidative stress. The dysregulation of many pathways and mechanisms regulated by inositols has been demonstrated in endocrine and neuroendocrine tumors but the role of inositol supplementation in this context has not been clarified. The aim of this review is to summarize the molecular basis of the possible role of inositols in endocrine and neuroendocrine tumors, proposing it as an adjuvant therapy.
Databáze:	Directory of Open Access Journals
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