Fast and accurate deformable contour propagation for intra-fraction adaptive magnetic resonance-guided prostate radiotherapy

Autor: Thomas Willigenburg, Cornel Zachiu, Jan J.W. Lagendijk, Jochem R.N. van der Voort van Zyp, Hans C.J. de Boer, Bas W. Raaymakers
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Physics and Imaging in Radiation Oncology, Vol 21, Iss , Pp 62-65 (2022)
Druh dokumentu: article
ISSN: 2405-6316
DOI: 10.1016/j.phro.2022.02.008
Popis: To facilitate full intra-fraction adaptive MR-guided radiotherapy, accurate contour propagation is needed. We aimed to assess the clinical usability of intra-fraction propagated contours by a deformable image registration algorithm in ten prostate cancer patients. Two observers judged the contours on need for manual adaptation and feasibility of adapting contours within 3 min. CTV and bladder contours needed none or only minor editing in most cases (≥ 97%), whereas rectum contours needed more extensive editing in 12–23%. Nevertheless, adaptation times were < 3 min for ≥ 93% of the cases. This paves the way for exploring adaptive workflows using intra-fraction deformable contour propagation.
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