| Autor: |
Mario Sádaba Sagredo, Asier Subinas Elorriaga, Sebastián Romaní Ménde, Daniel Valcárcel Paz, Rocío Angulo Llanos, Carlos Lara García, Alicia Quirós, Erika Muñoz García, Ángel Sánchez Recalde, Javier Robles Alonso, Fernando Lozano Ruiz-Poveda, Francisco Javier Irazusta, Alfredo Redondo, Rosa Alba Abellás Sequeiros, Oriol Rodríguez-Leor |
| Jazyk: |
English<br />Spanish; Castilian |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
REC: Interventional Cardiology (English Ed.), Vol 6, Iss 3, Pp 158-165 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2604-7322 |
| DOI: |
10.24875/RECICE.M24000446 |
| Popis: |
ABSTRACT Introduction and objectives: Functional assessment of coronary stenosis severity with the piezo-electric sensor pressure wire has shown a discrepancy of up to 20% between hyperemic and nonhyperemic indexes. No data are available with fiber-optic pressure wires. The aim of this study was to evaluate the incidence and factors related to the diagnostic discordance between these indexes with a fiber-optic pressure wire. Secondary aims were to assess diagnostic reproducibility in 2 consecutive measurements of fractional flow reserve (FFR) and diastolic pressure ratio (dPR) and evaluate the drift rate. Methods: We conducted a prospective, observational multicenter study in patients undergoing functional assessment with a fiber-optic pressure wire. We took 2 consecutive measurements of the dPR (cutoff point 0.89) and FFR (cut-off point 0.80) in each lesion analyzed. The diagnostic correlation between 2 measurements with the same technique and between the 2 techniques (dPR and FFR) was assessed. Clinical and angiographic factors associated with discordance (FFR−/dPR+ and FFR+/dPR−) between the 2 techniques were analyzed. Results: We included 428 cases of stenosis (361 patients). Diagnostic reproducibility was 95.8% for the dPR, with a correlation coefficient between the 2 measurements (dPR1 and dPR2) of 0.974 (P 60%. The drift rate was 5.7%. Conclusions: Although FFR and dPR measurements with a fiber-optic pressure wire have excellent reproducibility and a low drift rate, the discordance rate remains similar to those in previous studies with a piezo-electric pressure wire. FFR−/dPR+ discordance is associated with intracoronary adenosine and hypertension. FFR+/dPR− discordance is related to age < 75 years old and stenosis > 60%. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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