| Autor: |
Qiong Qin, Lin Yang, Yong-Kun Sun, Jian-Ming Ying, Yan Song, Wen Zhang, Jin-Wan Wang, Ai-Ping Zhou |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Chronic Diseases and Translational Medicine, Vol 3, Iss 1, Pp 51-59 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2095-882X |
| DOI: |
10.1016/j.cdtm.2017.02.004 |
| Popis: |
Objective: Recent studies have reported increased mortality for right-sided colon cancers; however, the results are conflicting for different stage tumors. We examined the differences in clinicopathology between right- and left-sided colon cancers and the relationships between colon cancer location (right- and left-side) and 5-year disease-free survival (DFS) and overall survival (OS). Methods: We identified patients from 2005 to 2008 with stage II/III colon cancer who underwent surgery for curative intent. We explored the impact of the tumor location on the postoperative DFS and OS using univariate and multivariate analyses. Results: Of 627 patients, 50.6% (317/627) had right-sided colon cancer. These patients were more likely to have weight loss, second primary tumor, elevated preoperative carbohydrate antigen 19-9 (CA19-9), increased incidence of non-adenocarcinoma, more poorly differentiated tumors, vascular invasion, defective mismatch repair, and a lighter smoking history (PÂ |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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