BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population

Autor: Kamyshna Iryna I., Pavlovych Larysa B., Sydorchuk Larysa P., Malyk Igor V., Kamyshnyi Aleksandr M.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Endocrine Regulations, Vol 55, Iss 4, Pp 193-203 (2021)
Druh dokumentu: article
ISSN: 1336-0329
DOI: 10.2478/enr-2021-0021
Popis: Objective. Brain-derived neurotrophic factor (BDNF) is identified as an important growth factor involved in learning and memory. Patients with Hashimoto’s thyroiditis can suffer from cognitive dysfunction, whereas BDNF is directly regulated by thyroid hormones. It seems reasonable to propose that changes in BDNF expression underlie some of the persistent neurological impairments associated with hypothyroidism.
Databáze: Directory of Open Access Journals