Autor: |
Pierre Frange, Thomas Montange, Jérôme Le Chenadec, Damien Batalie, Ingrid Fert, Catherine Dollfus, Albert Faye, Stéphane Blanche, Anne Chacé, Corine Fourcade, Isabelle Hau, Martine Levine, Nizar Mahlaoui, Valérie Marcou, Marie-Dominique Tabone, Florence Veber, Alexandre Hoctin, Thierry Wack, Véronique Avettand-Fenoël, Josiane Warszawski, Florence Buseyne |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Frontiers in Immunology, Vol 12 (2021) |
Druh dokumentu: |
article |
ISSN: |
1664-3224 |
DOI: |
10.3389/fimmu.2021.662894 |
Popis: |
BackgroundThe early initiation of antiretroviral therapy (ART) in HIV-1-infected infants reduces mortality and prevents early CD4 T-cell loss. However, the impact of early ART on the immune system has not been thoroughly investigated in children over five years of age or adolescents. Here, we describe the levels of naive CD4 and CD8 T lymphocytes (CD4/CD8TN), reflecting the quality of immune reconstitution, as a function of the timing of ART initiation (early ( |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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