Predictive model of electrical therapy failure in paroxysmal atrial fibrillation

Autor: Yoandro Rosabal Garcia, Eddy Alberto Rosales Guibert, lorchen Torres Quiñones
Jazyk: Spanish; Castilian
Rok vydání: 2023
Předmět:
Zdroj: Revista Cubana de Medicina Militar, Vol 52, Iss 4, Pp e02302831-e02302831 (2023)
Druh dokumentu: article
ISSN: 1561-3046
Popis: Introduction: Atrial fibrillation is the most common recurrent arrhythmia in clinical practice. Its prevalence is multiplying in the current population and has different pathophysiological causes that make it a global pandemic. Objectives: To design a predictive model for failure of electrical therapy in patients with paroxysmal atrial fibrillation. Methods: A case-control study was carried out with 33 cases, and 66 controls. Predictor variables: age, ejection fraction ≤ 40%, left atrial volume ≥ 34 mL/m2. From logistic regression, a model was obtained in which the positive predictive value, negative predictive value, sensitivity and specificity were included. Results: The predictive risk factors were: age ≥ 55 years (p= 0.013; odds ratio (OR)= 3.58; 95% confidence interval -CI-: 1.33-9.67); left ventricular ejection fraction (LVEF) ≤ 40% was observed in 20 patients (22.7%) (p= 0.004; OR= 4.45; 95% CI: 1.54-12.8); elevated left atrial pressure, elevated left atrial volume (p= 0.004; OR= 3.11; 95% CI: 1.24-8.77), according to the logistic regression model. Internal validation was carried out by data division; It was confirmed that the model predicts very well those who will be successful in the therapeutic result. Conclusions: The predictive model developed is composed of the predictors age > 55 years, LVEF; left atrial volume; It presents a good fit and discriminating power, especially positive predictive value.
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