Procalcitonin as an early marker in the detection of anastomotic intestinal leak in a Universitary Hospital of Bogotá

Autor: Elkin Eduardo Benítez Navarrete, Tatiana Carolina Beltrán-García, María Fernanda Mosquera, Valeria Martinez Rojas, Daniel Alejandro Buitrago Medina, Carlos Edgar Figueroa Avendaño
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Coloproctology, Vol 40, Iss 4, Pp 376-385 (2020)
Druh dokumentu: article
ISSN: 2237-9363
DOI: 10.1016/j.jcol.2020.07.005
Popis: Introduction: Anastomotic leakage is a complication of intestinal anastomosis, with an incidence of 2%–7% in centers of experience. To be able to achieve an early detection, serological markers such as Procalcitonin were included. Methods: Descriptive retrospective cohort study of patients taken to colorectal surgery with intestinal anastomosis, the objective is to estimate association between procalcitonin (≥2 ng/dl) as an early inflammatory marker and anastomotic leakage in a Coloproctological Service of a highest level of health care hospital, between September 2017 and January 2019. Results: Cohort of 237 patients, 51% women (18–89 years), with multiple comorbidities in 81% of patients, colon cancer was the most operated pathology (53.1%). Laparoscopic approach was the most applied 60.34%, colorectal anastomosis was the most frequently performed (47.26%). Ileocolic anastomosis presented a higher frequency (43.75%-n:7) of dehiscence. Anastomotic leakage was associated with a serum procalcitonin positive 3 days postoperatively (p-value
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