| Autor: |
Farzad Farajbakhsh, Mohammad Amjadi, Jamshid Manzoori, Mohammad R. Ardalan, Abolghasem Jouyban |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Pharmaceutical Sciences, Vol 22, Iss 2, Pp 87-95 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2383-2886 |
| DOI: |
10.15171/PS.2016.15 |
| Popis: |
Background: Analysis of aluminium (Al) in urine samples is required in management of a number of diseases including patients with renal failure. This work aimed to present dispersive liquid-liquid microextraction (DLLME) and ultrasound-assisted emulsification microextraction (USAEME) methods for the preconcentration of ultra-trace amount of aluminum in human urine prior to its determination by a graphite furnace atomic absorption spectrometry (GFAAS). Methods: The microextraction methods were based on the complex formation of Al3+ with 8-hydroxyquinoline. The effect of various experimental parameters on the efficiencies of the methods and their optimum values were studied. Results: Under the optimal conditions, the limits of detection for USAEME-GFAAS and DLLME-GFAAS were 0.19 and 0.30 ng mL−1, respectively and corresponding relative standard deviations (RSD, n=5) for the determination of 40 ng mL−1 Al3+ were 5.9% and 4.9%. Conclusion: Both methods could be successfully used to the analysis of ultra trace concentrations of Al in urine samples of dialysis patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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