Multifocal cutaneous phaeohyphomycosis caused by with clinical resolution in an immunocompromised cat
Autor: | Jevgenija Kondratjeva, Charline Pressanti, Brice S Reynolds, Catherine Trumel, Maxence Delverdier, Anne-Cécile Normand, Nicolas Soetart, Jacques Guillot, Marie Christine Cadiergues |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Feline Medicine and Surgery Open Reports, Vol 9 (2023) |
Druh dokumentu: | article |
ISSN: | 2055-1169 20551169 |
DOI: | 10.1177/20551169231164610 |
Popis: | Case summary A 3-year-old neutered domestic shorthair cat with a long history of idiopathic immune-mediated haemolytic anaemia and thrombocytopenia treated with ciclosporin and prednisolone was referred 2 months after the appearance of nodular dermatitis. A single pigmented nodule was present in the lateral carpal region of the right foreleg. The lesion was 7 mm in diameter, non-exudative and cutaneous to subcutaneous. Fine-needle aspiration of the mass revealed the presence of pigmented fungal elements. Excisional surgery was planned; in the meantime, a plaque-like lesion developed in the interorbital region. Histopathological examination confirmed the presumptive diagnosis of phaeohyphomycosis, and Exophiala spinifera was identified as the aetiological agent. Itraconazole, given orally at a dose of 10 mg/kg for 8 weeks following surgery, enabled clinical resolution despite continued use of immunosuppressants. The follow-up was carried out over 14 weeks. Relevance and novel information This case report provides the first evidence of multifocal cutaneous phaeohyphomycosis caused by E spinifera with clinical resolution after combined surgical and itraconazole treatment in an immunocompromised cat. |
Databáze: | Directory of Open Access Journals |
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