The Possible Relationship between Inflammation, Liver Dysfunction, and COVID-19 Severity: A cross-sectional study
Autor: | Maryam Dastfan, Ali Madadi Mahani, AmirAli Moodi Ghalibaf, Farid Poursadegh, Fariba Rezaeetalab, Ali Shamshirian, Mahnaz mozdorian |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Reviews in Clinical Medicine, Vol 11, Iss 2, Pp 36-43 (2024) |
Druh dokumentu: | article |
ISSN: | 2345-6256 2345-6892 |
DOI: | 10.22038/rcm.2024.80151.1496 |
Popis: | Background:The Coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges to healthcare systems worldwide. This cross-sectional study aimed to investigate the relationship between inflammatory markers, liver enzymes, lung involvement severity, and mortality in 841 COVID-19 patients admitted to Imam Reza Hospital affiliated to the Mashhad University of Medical Sciences, Mashhad, Iran.Methods:The study included demographic information, physical and clinical symptoms, laboratory findings, computed tomography (CT) scan scores, and final outcomes. Results:The mean age of the patients was 58.23±16.44 years, and 39.2% were female. The most common underlying disease was hypertension (51.3%), and the most frequent symptom at presentation was shortness of breath (87.1%). The mortality rate was 33.8%. The results showed a significant direct correlation between CRP levels and LDH levels (r=0.129, p |
Databáze: | Directory of Open Access Journals |
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