The Possible Relationship between Inflammation, Liver Dysfunction, and COVID-19 Severity: A cross-sectional study

Autor: Maryam Dastfan, Ali Madadi Mahani, AmirAli Moodi Ghalibaf, Farid Poursadegh, Fariba Rezaeetalab, Ali Shamshirian, Mahnaz mozdorian
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Reviews in Clinical Medicine, Vol 11, Iss 2, Pp 36-43 (2024)
Druh dokumentu: article
ISSN: 2345-6256
2345-6892
DOI: 10.22038/rcm.2024.80151.1496
Popis: Background:The Coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges to healthcare systems worldwide. This cross-sectional study aimed to investigate the relationship between inflammatory markers, liver enzymes, lung involvement severity, and mortality in 841 COVID-19 patients admitted to Imam Reza Hospital affiliated to the Mashhad University of Medical Sciences, Mashhad, Iran.Methods:The study included demographic information, physical and clinical symptoms, laboratory findings, computed tomography (CT) scan scores, and final outcomes. Results:The mean age of the patients was 58.23±16.44 years, and 39.2% were female. The most common underlying disease was hypertension (51.3%), and the most frequent symptom at presentation was shortness of breath (87.1%). The mortality rate was 33.8%. The results showed a significant direct correlation between CRP levels and LDH levels (r=0.129, p
Databáze: Directory of Open Access Journals