Driving assessment in preclinical Alzheimer’s disease: progress to date and the path forward

Autor:	Sayeh Bayat, Catherine M. Roe
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Alzheimer’s disease Preclinical Automobile driving Naturalistic GPS Mobile technology Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Zdroj:	Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-4 (2022)
Druh dokumentu:	article
ISSN:	1758-9193
DOI:	10.1186/s13195-022-01109-1
Popis:	Abstract Background Changes in driving behaviour may start at the preclinical stage of Alzheimer’s disease (AD), where the underlying AD biological process has begun in the presence of cognitive normality. Here, we summarize the emerging evidence suggesting that preclinical AD may impact everyday driving behaviour. Main Increasing evidence links driving performance and behaviour with AD biomarkers in cognitively intact older adults. These studies have found subtle yet detectable differences in driving associated with AD biomarker status among cognitively intact older adults. Conclusion Recent studies suggest that changes in driving, a highly complex activity, are linked to, and can indicate the presence of, neuropathological AD. Future research must now examine the internal and external validity of driving for widespread use in identifying biological AD.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/97b0ac253811495893795cf97e770acf Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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