Autor: |
Seybold Joachim, Wicker Sabine, Meier-Wronski Claus, Quarcoo David, Bias Harald, Nienhaus Albert, Groneberg David A, Roux Andres de |
Jazyk: |
angličtina |
Rok vydání: |
2011 |
Předmět: |
|
Zdroj: |
BMC Research Notes, Vol 4, Iss 1, p 297 (2011) |
Druh dokumentu: |
article |
ISSN: |
1756-0500 |
DOI: |
10.1186/1756-0500-4-297 |
Popis: |
Abstract Purpose The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. It was questioned if this is a safe vaccine. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods We focused on the H1N1 pandemic influenza vaccine Pandemrix® and applied a self reporting questionnaire in a population of healthcare workers (HCWs) and medical students at a major university hospital. Results In total, 4337 individuals were vaccinated, consisting of 3808 HCWs and 529 medical students. The vaccination rate of the employees was higher than 40%. The majority of individuals were vaccinated in November 2009. In total, 291 of the 4337 vaccinations were reported to lead to one or more adverse reactions (6.7%). Local reactions were reported in 3.8%, myalgia and arthralgia in 3.7%, fatigue in 3.7%, headache in 3.1%. Conclusions Our data together with available data from several national and international institutions points to a safe pandemic influenza vaccine. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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