Tumor-Specific Alterations in Motor Cortex Excitability and Tractography of the Corticospinal Tract—A Navigated Transcranial Magnetic Stimulation Study

Autor: Thomas Eibl, Michael Schrey, Adrian Liebert, Leonard Ritter, Rüdiger Lange, Hans-Herbert Steiner, Karl-Michael Schebesch
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Integrative Neuroscience, Vol 23, Iss 7, p 132 (2024)
Druh dokumentu: article
ISSN: 0219-6352
DOI: 10.31083/j.jin2307132
Popis: Background: Non-invasive brain mapping using navigated transcranial magnetic stimulation (nTMS) is a valuable tool prior to resection of malignant brain tumors. With nTMS motor mapping, it is additionally possible to analyze the function of the motor system and to evaluate tumor-induced neuroplasticity. Distinct changes in motor cortex excitability induced by certain malignant brain tumors are a focal point of research. Methods: A retrospective single-center study was conducted involving patients with malignant brain tumors. Clinical data, resting motor threshold (rMT), and nTMS-based tractography were evaluated. The interhemispheric rMT-ratio (rMTTumor/rMTControl) was calculated for each extremity and considered pathological if it was >110% or
Databáze: Directory of Open Access Journals