The influence of CASP8 D302H gene variant in colorectal cancer risk and prognosis

Autor: Cacina Canan, Turan Sürmen Saime, Arıkan Soykan, Pençe Sadrettin, Yaylım İlhan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Türk Biyokimya Dergisi, Vol 48, Iss 3, Pp 234-238 (2023)
Druh dokumentu: article
ISSN: 1303-829X
DOI: 10.1515/tjb-2022-0042
Popis: Apoptosis is defined as programmed cell death, which regulates cellular functions and various physiological responses. Several studies reported that Caspase genes play important roles in the apoptosis and inflammation process. Caspase-8 (CASP8) is a member of the cysteine protease family and a key regulator gene in the induction of apoptosis. In present study, we aimed to investigate the possible associations between the CASP8; D302H (G>C) gene polymorphism and colorectal cancer risk and prognosis.
Databáze: Directory of Open Access Journals