Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation

Autor: Marta Monist, Dorota Lewkowicz, Maciej Jóźwik, Marek Gogacz, Michał Bogusiewicz, Tomasz Rechberger, Andrzej Semczuk
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Oncology, Vol 12, Iss 1, Pp 317-321 (2019)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000499760
Popis: The incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopathological evidence of an early-stage malignant transformation in endometriotic tissue from a post-Cesarean scar and briefly reviews possible underlying mechanisms. A 40-year-old woman with a body mass index of 42.7 was referred to the gynecological department with recurrent pain and presence of a palpable mass in her Cesarean section scar. She had undergone this procedure 7 years earlier and began experiencing discomfort and pain at the incision site 6 months postoperatively. Surgical treatment was instituted with complete removal of the lesion. Anatomopathological examination revealed endometriotic tissue intertwined with atypical endometrial hyperplasia and fibrosis. At 2 years’ follow-up, she was asymptomatic, both clinically and based on ultrasound examination. Endometriotic foci inoculated within an abdominal scar may undergo malignant transformation. Long-lasting abdominal scar endometriosis, in morbidly obese women, requires special attention from the physician.
Databáze: Directory of Open Access Journals
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