POEMS Syndrome: Report of Three Cases with Review of the Literature

Autor: Somanath Padhi, Tara Roshni Paul, Rajlaxmi Sarangi, Shantveer Uppin, Sundaram Challa, Putcha Deekshanti Narayan
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Türk Nöroloji Dergisi, Vol 17, Iss 2, Pp 110-118 (2011)
Druh dokumentu: article
ISSN: 1301-062X
Popis: Polyneuropathy (P), organomegaly (O), endocrinopathy (E), monoclonal gammopathy (M), and skin changes(S) (POEMS) syndrome is a rare multisystemic disease that occurs in the setting of plasma cell dyscrasia. Several hundred cases have been reported in world literature. The exact prevalence is not known as the syndrome may be underreported. We reported three such cases (two males, one female) over a period of five years (January 2005 to December 2009). The clinicopathological, radiological, biochemical, and therapeutic outcome data of all the three cases are presented with a review of literature. Awareness about this entity and multidisciplinary approach is essential to make a diagnosis in these patients.
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