| Autor: |
Ana Maria Abreu Velez, Charles J Douchy, Michael S. Howard |
| Jazyk: |
English<br />Spanish; Castilian<br />French<br />Polish |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nasza Dermatologia Online, Vol 9, Iss 1, Pp 65-67 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2081-9390 |
| DOI: |
10.7241/ourd.20181.18 |
| Popis: |
Atypical (dysplastic) melanocytic nevi are considered for many as an intermediate step in a clinicopathologic spectrum. Regression is often seen. A 45 year old male presented with a hyperpigmented macule on the patient’s back. Biopsies for hematoxylin and eosin (H&E) examination and immunohistochemistry (IHC) analysis were performed. The H&E staining demonstrated a compound dysplastic nevus. IHC stain shows stains with galectin 3, CD45, B-cell lymphoma 2 cyclooxygenase-2 ribosomal protein S6-ps240 (RIBO), CD68 and tyrosinase. Some stains were not only present in the tumor, but around it. We described a case of compound dysplastic nevi with a likely effectual early antitumoral response avoiding the growth to melanoma. The fundamental mechanism has not been elucidated, but our findings indicate a mix of inflammatory as well as immune response mediators maybe involved in the immune-based obliteration of melanocytes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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