| Autor: |
Olutayo A. Sogunro, Rachael Steinhauer, Eugene Lewis |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Current Problems in Cancer: Case Reports, Vol 2, Iss , Pp 100041- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2666-6219 |
| DOI: |
10.1016/j.cpccr.2020.100041 |
| Popis: |
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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