Epidemiology of multidrug-resistant organisms before and during COVID-19 in Hong Kong

Autor: Shuk-Ching Wong, Pui-Hing Chau, Simon Yung-Chun So, Kelvin Hei-Yeung Chiu, Lithia Lai-Ha Yuen, Christine Ho-Yan AuYeung, Germaine Kit-Ming Lam, Veronica Wing-Man Chan, Jonathan Hon-Kwan Chen, Hong Chen, Xin Li, Pak-Leung Ho, Sophia Siu-Chee Chan, Kwok-Yung Yuen, Vincent Chi-Chung Cheng
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Infection Prevention in Practice, Vol 5, Iss 2, Pp 100286- (2023)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2023.100286
Popis: SUMMARY: Background: The coronavirus disease 2019 (COVID-19) has influenced antimicrobial consumption and incidence of multidrug-resistant organisms (MDROs). We aimed to study the epidemiology of MDROs before and during the COVID-19 pandemic in Hong Kong. Methods: With the maintenance of infection control measures, we described the trend of MDRO infections, including methicillin-resistant Staphylococcus aureus (MRSA), carbapenem-resistant Acinetobacter species (CRA), and extended-spectrum-beta-lactamase-(ESBL)-producing Enterobacterales, in a healthcare region with 3100-bed before (1 January 2016 to 31 December 2019, period 1) and during COVID-19 (1 January 2020 to 30 September 2022, period 2), together with the antimicrobial consumption using piecewise Poisson regression. The epidemiological characteristics of newly diagnosed COVID-19 patients with or without MDRO infections were analyzed. Results: Between period 1 and 2, we observed a significant increase in the trend of CRA infections (P
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