Lamotrigine induced priapism in children: case analysis and literature review

Autor: Jie Ge, Shan-Shan Cao, Xiao-Yu Cao, Meng Tang, Fei Mu, Yi Qiao, Yue Guan, Jing-Wen Wang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of International Medical Research, Vol 50 (2022)
Druh dokumentu: article
ISSN: 1473-2300
03000605
DOI: 10.1177/03000605221133988
Popis: Lamotrigine is an antiepileptic drug that can be used to control many types of seizures as a single-agent or an add-on therapy in patients over 2 years of age. In addition to common adverse reactions, this current case report describes a paediatric male patient with a rare side-effect of persistent penile erectile due to lamotrigine. Previous studies have shown that it can improve sexual function in adult male patients. This patient suffered from refractory epilepsy and pneumonia. He had taken a variety of antiepileptic drugs for a long time and developed priapism after the dosage of lamotrigine had been increased. The priapism improved after drug withdrawal and sedation. Further research is needed to elucidate the mechanism of this rare side-effect.
Databáze: Directory of Open Access Journals