Secondary Haemophagocytic Lymphohistiocytosis Syndrome (HLH) After Intravesical Instillation of Bacillus Calmette-Guérin (BCG): A Case Report and Review of the Literature

Autor: Konstantinos Manganas, Angelara Maria, Ioanna Bountzona, George Karamanakos, Angelos Toskas
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2022)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2022_003395
Popis: Intravesical bacillus Calmette-Guérin (BCG) instillation is widely used for the treatment of superficial bladder cancer. BCGitis is a serious immune-mediated complication with systematic manifestations and a high mortality rate. Here, we describe a case of a 64-year-old male patient who presented with haemophagocytic lymphohistiocytosis syndrome (HLH) after BCG instillation and was effectively treated with high-dose dexamethasone, intravenous immunoglobulins and anti-tuberculosis treatment.
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