THE ROLE OF DIFFUSION-WEIGHTED MRI OF PATIENTS WITH SPINE METASTASES

Autor: Vadim Anatol'evich Byvaltsev, Ivan Andreevich Stepanov, Alexander Ivanovich Kichigin
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2019
Předmět:
Zdroj: Coluna/Columna, Vol 18, Iss 4, Pp 289-293 (2019)
Druh dokumentu: article
ISSN: 2177-014X
1808-1851
DOI: 10.1590/s1808-185120191804225382
Popis: ABSTRACT Objective: The role of diffusion-weighted MRI in differential diagnostics and predicting the survival of patients with spine metastases was studied. Methods: The study included data from MRI and morphological studies of 23 patients with spine metastases. Results: The values obtained for the apparent diffusion coefficient (ADC) of tumors were compared with their histological type, cell density and Ki-67 proliferation index. The effect of ADC values on overall patient survival was also assessed. A reliable inverse correlation was established between ADC values and Ki-67 proliferation index for various types of spine metastases (r=-0.753, p=0.017). The dependence of ADC values and overall survival of patients with metastases in the spine is shown. Conclusion: The technique of diffusion-weighted MRI can be used as part of a comprehensive assessment in the preoperative planning of surgical treatment, and as a prognostic factor of overall survival for this group of patients. Level of Evidence II. Prognostic retrospective study,
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