Controlling protein activity by dynamic recruitment on a supramolecular polymer platform

Autor: Sjors P. W. Wijnands, Wouter Engelen, René P. M. Lafleur, E. W. Meijer, Maarten Merkx
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-02559-0
Popis: DNA-origami allows the precise recruitment of DNA-protein conjugates but lacks the dynamics found in natural protein assemblies. Here the authors present a synthetic polymer platform that combines the dynamics of supramolecular polymers with the programmability of DNA-mediated protein recruitment.
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