CD4 count, viral load and parasite density of HIV positive individuals undergoing malaria treatment with dihydroartemisinin in Benin City, Edo state, Nigeria

Autor: Y.M. Tatfeng, J.C. Ihongbe, M. Okodua, F. Oviasogie, J. Isibor, S. Tchougang, E. Tambo , T. Otegbeye
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Journal of Vector Borne Diseases, Vol 44, Iss 2, Pp 111-115 (2007)
Druh dokumentu: article
ISSN: 0972-9062
Popis: Background & objectives: A prospective study on 72 HIV infected and 33 HIV negative individualsundergoing malaria treatment with dihydroartemisinin (Cotecxin) was undertaken to compare CD4cells count, viral load and parasite density at two time-points, a baseline visit and a 9-day posttreatmentvisit.Methods: CD4 count and viral load of the subjects were estimated using Dynabeads T4–T8Quantification Protocol (Dyneal Biotech, Norway) and Amplicor HIV-1 Monitor Test respectively(Roche, United Kingdom).Results: There was a significant decrease in CD4 count at 9-day post-treatment when compared withbaseline value (p 200 cells/μl, a marked significant increase was obtained when the mean viral loadat baseline was compared to the 9-day post-treatment visit value (p
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