Synthesis of Novel Sterically Demanding Carbo- and Heterocyclic β-Ketoesters
| Autor: | Peter Stanetty, Thomas C. M. Fischer, Marko D. Mihovilovic |
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| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Molecules, Vol 11, Iss 5, Pp 357-364 (2006) |
| Druh dokumentu: | article |
| ISSN: | 11050357 1420-3049 |
| DOI: | 10.3390/11050357 |
| Popis: | We present an easy method for the synthesis of β-ketoesters starting from variouscarbocyclic and heterocyclic carboxylic acids and esters. The β-ketoester side-chain wasintroduced by a sequence involving α-deprotonation and quenching with CO2, conversion tothe corresponding acid chloride and subsequent chain elongation using deprotonated ethylacetate. |
| Databáze: | Directory of Open Access Journals |
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