Mitochondrial Dysfunction in Advanced Maternal Aged Cumulus Cells: A Possible Link to ATP Synthase Impairment?

Autor:	Sandra Almeida-Reis, Alexandra Carvalho, Conceição Dias, Raquel Brito, Rita Silva, Teresa Almeida-Santos, João Ramalho-Santos, Ana Paula Sousa
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	maternal aging cumulus cells mitochondria oxidative phosphorylation ATP synthase Microbiology QR1-502
Zdroj:	Biomolecules, Vol 14, Iss 3, p 281 (2024)
Druh dokumentu:	article
ISSN:	2218-273X
DOI:	10.3390/biom14030281
Popis:	Age-related changes in the mitochondrial status of human cumulus cells (hCCs) impact oocyte quality; however, the relationship between hCC mitochondrial (dys)function and reproductive aging remains poorly understood. This study aimed to establish the interplay between hCC mitochondrial dysfunction and women’s reproductive potential. In this investigation, 266 women were enrolled and categorized into two groups based on their age: a young group (
Databáze:	Directory of Open Access Journals
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