Atypical spindle cell lipomatous tumour presenting as a large retroperitoneal mass – a case report and review of the literature
| Autor: | Martyna Krupinska, Carmen León, Rocío López Henríquez, Beatriz Esquivel Vázquez, Rosa Nieves Rodríguez Rodríguez, Patricia Marrero Marrero, Luciano Delgado Plasencia, Eduardo Salido |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Polish Journal of Pathology, Vol 73, Iss 4, Pp 364-370 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1233-9687 2084-9869 |
| DOI: | 10.5114/pjp.2022.125654 |
| Popis: | Atypical spindle cell lipomatous tumour (ASCLT) is a benign neoplasm that presents a variable proportion of atypical spindle and adipocytic cells, frequently expressing CD34, and embedded in myxoid or collagenous matrix. An important feature is a constant lack of either MDM2 or CDK4 amplification. It typically arises in the extremities. The retroperitoneum is a rare site of involvement. We report a case of a retroperitoneal ASCLT in a 62-year-old male. A differential diagnosis of ASCLT from the other mesenchymal, spindle-cell, and lipomatous tumours is crucial for optimal treatment and significantly influences the prognosis. A diagnosis should be warranted by the immunohistochemistry and molecular findings. |
| Databáze: | Directory of Open Access Journals |
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