| Autor: |
Kwan Celia, Bhatt Mihir D., Strike Karen, Decker Kay, Matino Davide, Chan Anthony K.C. |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
The Journal of Haemophilia Practice, Vol 8, Iss 1, Pp 80-85 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2055-3390 |
| DOI: |
10.17225/jhp00179 |
| Popis: |
Current treatment for severe haemophilia includes prophylactic factor replacement to prevent bleeding. Coagulation factor products have significant inter-patient variability in pharmacokinetic (PK) parameters. Optimal management requires tailoring prophylaxis to individual PK parameters. Web-based Application for the Population Pharmacokinetic Service (WAPPS) is a tool that estimates individual PK values using a population approach. Despite its growing use to help guide dosing selection, few studies have investigated its clinical impact. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
