HPLC determination, pharmacokinetics and relative bioavailability of levofloxacin produced by «OZONE», Russia

Autor:	S. N. Kondratenko, A. K. Starodubtcev, E. A. Senik, O. V. Dralova, S. N. Kudinova
Jazyk:	ruština
Rok vydání:	2013
Předmět:	левофлоксацин вэжх плазма крови фармакокинетика биодоступность биоэквивалентность воспроизведённые препараты дженерик levofloxacin hplc blood plasma pharmacokinetics bioavailability bioequivalence generic drugs generic Pharmacy and materia medica RS1-441
Zdroj:	Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 23-26 (2013)
Druh dokumentu:	article
ISSN:	2587-7836 2686-8830
Popis:	A simple, specific, sensitive and reproducible good method for quantitative determination of Levofloxacin in plasma using HPLC with UV-spectrophotometric detection. With this technique the pharmacokinetics and relative bioavailability of domestic generic of levofloxacin in 18 healthy volunteers after a single oral dose of 500 mg. Found that the drug being tested, levofloxacin (OOO «Ozone», Russia) is bioequivalent to the reference drugs Tavanic® («Sanofi Winthrop Industry», France).
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/96b39403178d496ca5db682e2795feca Zobrazit plný text záznamu View record in DOAJ