Association of RT-qPCR Ct Values and Disease Severity among COVID-19 Patients Visiting a Tertiary Care Hospital in Nepal
| Autor: | Jagadish Joshi, Om Prakash Joshi, Sher Bahadur Kamar, Guna Raj Awasthi, Yogendra Shah, Ramesh Shahi, Sandip Khadka, Hem Raj Joshi, Pushpa Raj Padhaya, Chet Raj Joshi, Ram Prashad Ojha, Sunil Bahadur Singh, Lok Raj Bhatt, Ram Singh Dhami, Kishor Pandey, Sudip Regmi, Sita Ram Sapkota, Dhan Kumar Pant, Kamal Singh Khadka, Shyam Prakash Dumre, Basu Dev Pandey |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Pure and Applied Microbiology, Vol 18, Iss 1, Pp 662-671 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0973-7510 2581-690X |
| DOI: | 10.22207/JPAM.18.1.51 |
| Popis: | COVID-19 pandemic due to SARS-CoV-2 has been one of the major global health issues of this aeon. The aim of this study was to evaluate the association of SARS-CoV-2 cycle threshold (Ct) values with multiple factors among COVID-19 patients visiting a tertiary care hospital in Sudurpashchim province of Nepal. A retrospective analysis was performed on the data of randomly selected COVID-19 cases among the total RT-qPCR tested patients from March 2020 to April 2022. The Ct values at the time of patient admission and their clinical outcomes (discharge or death) were compared. Among the COVID-19 patients, survivor group had significantly higher initial Ct value compared to non-survivors [median Ct values 23.21 and 24.39 (P < 0.0001)]. Selected haematological parameters; white blood cells (P |
| Databáze: | Directory of Open Access Journals |
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