Relationship of Late Lactation Milk Somatic Cell Count and Cathelicidin with Intramammary Infection in Small Ruminants

Autor: Giulia Maria Grazia Puggioni, Vittorio Tedde, Sergio Uzzau, Simone Dore, Manuele Liciardi, Eugenia Agnese Cannas, Claudia Pollera, Paolo Moroni, Valerio Bronzo, Maria Filippa Addis
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Pathogens, Vol 9, Iss 1, p 37 (2020)
Druh dokumentu: article
ISSN: 2076-0817
DOI: 10.3390/pathogens9010037
Popis: Late lactation is a critical moment for making mastitis management decisions, but in small ruminants the reliability of diagnostic tests is typically lower at this stage. We evaluated somatic cell counts (SCC) and cathelicidins (CATH) in late lactation sheep and goat milk for their relationship with intramammary infections (IMI), as diagnosed by bacteriological culture (BC). A total of 315 sheep and 223 goat half-udder milk samples collected in the last month of lactation were included in the study. IMI prevalence was 10.79% and 15.25%, respectively, and non-aureus staphylococci were the most common finding. Taking BC as a reference, the diagnostic performance of SCC and CATH was quite different in the two species. In sheep, receiver operating characteristic (ROC) analysis produced a higher area under the curve (AUC) value for CATH than SCC (0.9041 versus 0.8829, respectively). Accordingly, CATH demonstrated a higher specificity than SCC (82.92% versus 73.67%, respectively) at comparable sensitivity (91.18%). Therefore, CATH showed a markedly superior diagnostic performance than SCC in late lactation sheep milk. In goats, AUC was
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