Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome

Autor: M.M. Gridina, E.M. Shitik, N.A. Lemskaya, J.M. Minina, I.V. Grishchenko, A.A. Dolskiy, A.R. Shorina, Y.V. Maksimova, D.V. Yudkin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Stem Cell Research, Vol 57, Iss , Pp 102615- (2021)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2021.102615
Popis: Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers.
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