| Autor: |
I Nengah Sujaya, Ida Ayu Gde Wahyudevi Dharmika, Gede Ngurah Rsi Suwardana, I Ketut Mariadi, I Gusti Kamasan Nyoman Arijana, Ida Bagus Oka Winaya, Komang Ayu Nocianitri, Yan Ramona, Ni Nengah Dwi Fatmawati |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1756-0500 |
| DOI: |
10.1186/s13104-023-06456-2 |
| Popis: |
Abstract Objective This study was performed to investigate the potential effects of Weissella confusa F213 (WCF213) on chemically-induced colitis rats. Twelve male Wistar rats were divided into three groups: T1 (saline sterile), T2 (2.5% dextran sulfate sodium (DSS)- for 7 days), and T3 (WCF213 for 14 days, continued with 2.5% DSS for 7 days). The disease activity index (DAI) was monitored. After sacrificing the rats, the colon was collected for length measurement, local TNF-α level, HE staining for histology, and ZO-1 expression by using immunohistochemistry. Results WCF213 administration prevented weight loss and haematochezia, maintained average colon length and alleviated the clinical symptom of colitis, such as diarrhoea, albeit statistically non-significant (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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