Off-label uses of etanercept in dermatology
| Autor: | Andrés Tirado-Sánchez, Victoria de la Fuente-García, Rosa María Ponce-Olivera |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Revista Médica del Hospital General de México, Vol 79, Iss 1, Pp 26-32 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0185-1063 43298176 |
| DOI: | 10.1016/j.hgmx.2015.10.005 |
| Popis: | Tumour necrosis factor alpha (TNFα) is a key molecule involved in the inflammatory response and thus related to the pathogenesis of several autoimmune and autoinflammatory diseases. The blockade of TNF receptor (etanercept main effect) has been successfully used in psoriasis and psoriatic arthritis, among other rheumatologic diseases. The only approved indication for etanercept in dermatological disease is plaque psoriasis; however, the literature is full of case reports and case series where etanercept was used off-label, sometimes successfully. We review some of these indications. |
| Databáze: | Directory of Open Access Journals |
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