| Autor: |
Leandro Martin Castillo, Gabriela Bugarin, Juan Carlos Arias, Jairo Israel Barajas Rangel, Maria Elina Serra, Nestor Vain |
| Jazyk: |
portugalština |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Jornal de Pediatria (Versão em Português), Vol 93, Iss 5, Pp 467-474 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2255-5536 |
| DOI: |
10.1016/j.jpedp.2017.02.014 |
| Popis: |
Objective: This study aims to describe real world palivizumab use and effectiveness in high‐risk Latin American infants and young children. Method: Prospective, multicenter observational study with infants at risk for severe RSV infection who received palivizumab according to routine clinical practice. Subjects were followed for one year with monthly visits after the first dose of palivizumab. An infant was considered adherent if receiving all the expected injections or five or fewer injections within appropriate inter‐dose intervals. Annual incidence rates and risk factors of lower respiratory tract infection (LRTI) hospitalization were determined through Poisson regression models (α = 0.05). Results: The study enrolled 458 children from seven countries in Latin America, from February 2011 to September 2012. The majority (98%) were born |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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