| Autor: |
Myung Hee Kim, Hyun Yong Jeong, Jae Kyu Seong, Hee Seok Moon, Sun Hyung Kang, Duk Ki Kim |
| Jazyk: |
English<br />Korean |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
The Korean Journal of Gastroenterology, Vol 68, Iss 5, Pp 265-269 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1598-9992 |
| DOI: |
10.4166/kjg.2016.68.5.265 |
| Popis: |
Neuroendocrine tumors (NETs) of the esophagus are extremely rare, aggressive and have a poor prognosis. Combined therapy using chemotherapy, radiotherapy and/or surgery appear effective. Here, we present a patient with a complaint of dysphagia who was diagnosed with this rare tumor. Upper gastrointestinal endoscope of a 46-year-old female revealed a localized ulcerative lesion in the middle esophagus. Histologic exam of biopsy specimens indicated a neuroendocrine carcinoma. The tumor cells were arranged in microtubular structures, with small and round cells containing scanty cytoplasm. They were positive for synaptophysin and chromogranin A on immunohistochemical staining. A computed tomography scan showed an esophageal tumor with enlarged superior mediastinal lymph nodes and about 1.2 cm sized liver metastasis, similar to findings in PET-CT scanning. The patient was prescribed chemotherapy consisting of etoposide and cisplatin, which led to regression of disease on follow-up imaging study. She continues under clinical observation. We seek to increase awareness of this exceedingly rare but hazardous disease by sharing our unexpected finding. (Korean J Gastroenterol 2016;68:265-269) |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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