Comprehensive Cardiac Magnetic Resonance for Short‐Term Follow‐Up in Acute Myocarditis

Autor: Julian A. Luetkens, Rami Homsi, Darius Dabir, Daniel L. Kuetting, Christian Marx, Jonas Doerner, Ulrike Schlesinger‐Irsch, René Andrié, Alois M. Sprinkart, Frederic C. Schmeel, Christian Stehning, Rolf Fimmers, Juergen Gieseke, Claas P. Naehle, Hans H. Schild, Daniel K. Thomas
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.116.003603
Popis: BackgroundCardiac magnetic resonance (CMR) can detect inflammatory myocardial alterations in patients suspected of having acute myocarditis. There is limited information regarding the degree of normalization of CMR parameters during the course of the disease and the time window during which quantitative CMR should be most reasonably implemented for diagnostic work‐up. Methods and ResultsTwenty‐four patients with suspected acute myocarditis and 45 control subjects underwent CMR. Initial CMR was performed 2.6±1.9 days after admission. Myocarditis patients underwent CMR follow‐up after 2.4±0.6, 5.5±1.3, and 16.2±9.9 weeks. The CMR protocol included assessment of standard Lake Louise criteria, T1 relaxation times, extracellular volume fraction, and T2 relaxation times. Group differences between myocarditis patients and control subjects were highest in the acute stage of the disease (P
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