Six-month follow-up of functional status in discharged patients with coronavirus disease 2019

Autor: Hou-wei Du, Shuang-fang Fang, Sang-ru Wu, Xiao-ling Chen, Jun-nian Chen, Yi-xian Zhang, Hua-yao Huang, Han-han Lei, Rong-hua Chen, Xiao-bin Pan, Xiao-qing Li, Pin-cang Xia, Zhen-yang Zheng, Ling-Luo, Hai-long Lin, Li-min Chen, Nan Liu, Fujian Medical Team Support Wuhan for COVID
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-021-06970-3
Popis: Abstract Background The long-term functional outcome of discharged patients with coronavirus disease 2019 (COVID-19) remains unresolved. We aimed to describe a 6-month follow-up of functional status of COVID-19 survivors. Methods We reviewed the data of COVID-19 patients who had been consecutively admitted to the Tumor Center of Union Hospital (Wuhan, China) between 15 February and 14 March 2020. We quantified a 6-month functional outcome reflecting symptoms and disability in COVID-19 survivors using a post-COVID-19 functional status scale ranging from 0 to 4 (PCFS). We examined the risk factors for the incomplete functional status defined as a PCFS > 0 at a 6-month follow-up after discharge. Results We included a total of 95 COVID-19 survivors with a median age of 62 (IQR 53–69) who had a complete functional status (PCFS grade 0) at baseline in this retrospective observational study. At 6-month follow-up, 67 (70.5%) patients had a complete functional outcome (grade 0), 9 (9.5%) had a negligible limited function (grade 1), 12 (12.6%) had a mild limited function (grade 2), 7 (7.4%) had moderate limited function (grade 3). Univariable logistic regression analysis showed a significant association between the onset symptoms of muscle or joint pain and an increased risk of incomplete function (unadjusted OR 4.06, 95% CI 1.33–12.37). This association remained after adjustment for age and admission delay (adjusted OR 3.39, 95% CI 1.06–10.81, p = 0.039). Conclusions A small proportion of discharged COVID-19 patients may have an incomplete functional outcome at a 6-month follow-up; intervention strategies are required.
Databáze: Directory of Open Access Journals
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