| Autor: |
Enrique Canelles, Juan Carlos Bernal, Juan Berasategui, José Puche, Francisco Javier Landete, Leonardo de-Tursi |
| Jazyk: |
English<br />Spanish; Castilian |
| Předmět: |
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| Zdroj: |
Revista Espanola de Enfermedades Digestivas, Vol 107, Iss 4, Pp 216-220 |
| Druh dokumentu: |
article |
| ISSN: |
1130-0108 |
| Popis: |
Introduction: Calcium channel blockers have an excellent effectiveness in the conservative management of chronic anal fissure (CAF). Objectives: To assess the long-term results of management with diltiazem 2% ointment using a telephone questionnaire. Methods: A descriptive, retrospective study from March 2004 to March 2011 in patients with CAF on diltiazem 2%, 3 applications daily for 4-6 weeks. Starting at 12 months a questionnaire was administered over the phone by medical staff outside the surgery department to record socio-demographic data, predominant manifestations, and response to diltiazem on a 5-point scale measuring symptom relief (1 = poorest, 5 = best). Patients with therapy failure were referred to surgery. Results: The study was completed for 166 patients with a mean age of 54.1 years. CAF was posterior in 82.3% of subjects. Diltiazem tolerability was excellent with only 4 adverse event cases (3 skin irritation, 1 hypotension). We obtained symptom relief in 62.1% of patients and CAF healing in 51.2%, and referred 33.7% to surgery. The questionnaire showed that 74.1% of patients had used only 2 applications daily, and that results were better with an increased number of applications, albeit without statistical significance. Conclusions: The telephone questionnaire showed symptom relief for 62% and healing for 51.2% of patients with CAF on diltiazem 2%, which should be considered first-choice for the conservative management of this condition. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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