Meta-analysis of the Clinical Efficacy and Safety of Treating Amyotrophic Lateral Sclerosis Based on the Theory of Deficient Qi Induced Stagnation

Autor: Xu Mengfang, Xu Tianjiao, Zhang Muzhao, Han Xiao, Wu Linlu, Chen Tianzhu, Ma Renzhao, Zou Yihuai
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Guoji laonian yixue zazhi, Vol 45, Iss 6, Pp 689-697 (2024)
Druh dokumentu: article
ISSN: 1674-7593
DOI: 10.3969/j.issn.1674-7593.2024.06.009&lang=en
Popis: Objective To systematically evaluate the efficacy and safety of treating amyotrophic lateral sclerosis(ALS) based on the theory of “Deficient Qi Induced Stagnation”. Methods CNKI, Wangfang Data, VIP, CBM, PubMed, Embase, Cochrane Library, Web of Science were searched to collect randomized controlled trials of treating ALS based on the theory of “deficient qi induced stagnation” applying the method of replenishing deficiency and passing stagnation for the treatment of ALS published from the establishment of the databases to October 2023. Meta analysis was performed using Revman Manager 5.4 software and Stata 18 software. Results A total of 14 randomized controlled studies involving 844 patients were identified. The total effective rate and ALS functional scale score of combined therapy of traditional Chinese and western medicine in the intervention group were higher than those in the control group (P0.05). Conclusion Treatment of ALS based on the theory of “Deficient Qi Induced Stagnation” can effectively slow down the disease progression, improve neurological function, improve the quality of life, and doesn’s increase the occurrence of adverse effects.
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