Multi-omics analysis reveals the molecular regulatory network underlying the prevention of Lactiplantibacillus plantarum against LPS-induced salpingitis in laying hens

Autor:	Dan Song, Aike Li, Bingxu Chen, Jia Feng, Tao Duan, Junlin Cheng, Lixian Chen, Weiwei Wang, Yuna Min
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Laying hen Metabolome Microbiome Microencapsulated Lactiplantibacillus plantarum Salpingitis Transcriptome Animal culture SF1-1100 Veterinary medicine SF600-1100
Zdroj:	Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-15 (2023)
Druh dokumentu:	article
ISSN:	2049-1891
DOI:	10.1186/s40104-023-00937-x
Popis:	Abstract Background Salpingitis is one of the common diseases in laying hen production, which greatly decreases the economic outcome of laying hen farming. Lactiplantibacillus plantarum was effective in preventing local or systemic inflammation, however rare studies were reported on its prevention against salpingitis. This study aimed to investigate the preventive molecular regulatory network of microencapsulated Lactiplantibacillus plantarum (MLP) against salpingitis through multi-omics analysis, including microbiome, transcriptome and metabolome analyses. Results The results revealed that supplementation of MLP in diet significantly alleviated the inflammation and atrophy of uterus caused by lipopolysaccharide (LPS) in hens (P
Databáze:	Directory of Open Access Journals
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