| Autor: |
Zhongyuan Li, Jinwen Huang, Zhuang Ni, Ran Sun, Hui Nie, Hui Tang, Lixing Song, Fanhong Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
SynOpen, Vol 06, Iss 01, Pp 19-30 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2509-9396 |
| DOI: |
10.1055/s-0040-1719888 |
| Popis: |
Indium can efficiently mediate the Reformatsky reaction of iododifluoroacetylketones with aldehydes to afford the corresponding α,α-difluoro-β-hydroxyketones in high yield in pure water This reaction has excellent substrate suitability and functional group selectivity and provides an efficient approach for the synthesis of bioactive molecules containing the α,α-difluoro-β-hydroxyketone pharmacophore. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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