| Autor: |
Danuta Mazurel, Miguel Carda-Diéguez, Thomas Langenburg, Miglė Žiemytė, William Johnston, Carlos Palazón Martínez, Fernando Albalat, Carmen Llena, Nezar Al-Hebshi, Shauna Culshaw, Alex Mira, Bob T. Rosier |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-12 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5008 |
| DOI: |
10.1038/s41522-023-00406-3 |
| Popis: |
Abstract A few studies indicate that nitrate can reduce dysbiosis from a periodontitis point of view. However, these experiments were performed on samples from healthy individuals, and it is unknown if nitrate will be effective in periodontal patients, where the presence of nitrate-reducing bacteria is clearly reduced. The aim of this study was to test the effect of nitrate and a nitrate-reducing R. aeria (Ra9) on subgingival biofilms of patients with periodontitis. For this, subgingival plaque was incubated with 5 mM nitrate for 7 h (n = 20) or 50 mM nitrate for 12 h (n = 10), achieving a ~50% of nitrate reduction in each case. Additionally, Ra9 was combined with 5 mM nitrate (n = 11), increasing the nitrate reduced and nitrite produced (both p 5 mM, both p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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