Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration

Autor: Kazuma Kamata, Yuki Otsuka, Keiko Imamura, Akio Oishi, Takayuki Kondo, Mika Suga, Ran Shibukawa, Yasue Okanishi, Yukako Sagara, Kayko Tsukita, Tsutomu Yasukawa, Hideaki Usui, Keiko Muguruma, Akitaka Tsujikawa, Haruhisa Inoue
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Stem Cell Research, Vol 45, Iss , Pp - (2020)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2020.101787
Popis: Age-related macular degeneration (AMD) is a late-onset progressive blinding disease. We established human induced pluripotent stem cells (iPSCs) from an AMD patient. The generated iPSC line showed pluripotency markers and three-germ layer differentiation ability in vitro. This iPSC line will be useful for elucidating the pathomechanisms of and drug discovery for AMD.
Databáze: Directory of Open Access Journals