Xpert MTB/RIF assay for diagnosis of extrapulmonary tuberculosis in children: a systematic review and meta-analysis

Autor:	Young Seok Seo, Ji-Man Kang, Dong Soo Kim, Jong Gyun Ahn
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Extrapulmonary tuberculosis Xpert MTB/RIF Child Meta-analysis Infectious and parasitic diseases RC109-216
Zdroj:	BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
Druh dokumentu:	article
ISSN:	1471-2334
DOI:	10.1186/s12879-019-4745-1
Popis:	Abstract Background The Xpert® MTB/RIF assay (Xpert; Cepheid, Sunnyvale, CA, USA) is a cartridge-based nucleic acid amplification assay for rapidly diagnosing tuberculosis and assessing antibiotic sensitivity. Although previous evidence supports the use of Xpert for diagnosing extrapulmonary tuberculosis (EPTB) in adults, information regarding the accuracy of Xpert for EPTB only in children is lacking. This meta-analysis was performed to assess the accuracy of Xpert for detecting EPTB in children. Methods We searched the MEDLINE, EMBASE, and Cochrane Infectious Diseases Group Specialized Register from January 1, 2010 to July 16, 2019 for studies of the diagnostic performance wherein Xpert was analyzed against cultures or composite reference standards for
Databáze:	Directory of Open Access Journals
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