| Autor: |
Krishna Deepti Mogili, Hepsy Y. Selliah, Achamma Chandy, Aleyamma T. Kunjummen, Mohan S. Kamath |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Middle East Fertility Society Journal, Vol 23, Iss 2, Pp 93-97 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1110-5690 |
| DOI: |
10.1016/j.mefs.2017.09.007 |
| Popis: |
Objective: The purpose of this study was to evaluate whether poor responder women have adverse perinatal outcomes compared to normo responders following assisted reproductive technology (ART). Methods: A retrospective cohort study was conducted in a university level infertility unit between January 2010 to December 2015. Women undergoing fresh IVF cycles were included. Poor responders (≤3 oocytes) and normo responders (4–15 oocytes) were analyzed. Perinatal outcomes such as preterm birth (PTB), low birth weight (LBW), early preterm birth (early PTB) and very low birth weight (very LBW) were recorded. Results: A total of 1386 ART cycles were analyzed. Final analysis included 40 and 318 live births in poor and normo responders respectively. The risk of PTB (30.3% vs. 24.8%; OR 1.32, 95% CI: 0.59–2.9), LBW (33.3% vs. 20.1%; OR 1.99, 95% CI 0.90–4.4), early PTB (3% vs. 2.2%; OR 1.40, 95% CI 0.16–12.4) and very LBW (3% vs. 1.8%: OR 1.72, 95% CI 0.19–15.9) were not significantly different between poor and normo responders. The subgroup analysis within poor responders did not show any significant difference in perinatal outcomes in women aged less and more than 35 years. Conclusion: The current study findings suggest no increased risk of adverse perinatal outcomes in poor responders compared to normo responders following ART. These findings need to be further validated by larger studies. Keywords: Poor responder, Normo responder, Perinatal outcomes |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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