Opioid dependence and substitution therapy: thymoquinone as potential novel supplement therapy for better outcome for methadone maintenance therapy substitution therapy
| Autor: | Liyana Hazwani Mohd Adnan, Nor Hidayah Abu Bakar, Nasir Mohamad |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Iranian Journal of Basic Medical Sciences, Vol 17, Iss 12, Pp 926-928 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2008-3866 2008-3874 |
| Popis: | Methadone is widely being used for opioid substitution therapy. However, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. Other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. This article is written to higlights the potential use of prophetic medicines, Nigella sativa, as a supplement for opioid dependent receiving methadone. It focuses on the potential role of N. sativa and its major active compound, Thymoquinone (TQ) as a calcium channel blocking agent to reduce withdrawal syndrome and opioid dependency. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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